Diagnostic capacity of colposcopy and cytology in screening for uterine cervix
DOI:
https://doi.org/10.35434/rcmhnaaa.2023.164.2129Keywords:
Papanicolaou test, colposcopy, cervical intraepithelial neoplasia, sensitivity and specificityAbstract
Introduction: Cervical cancer is one of the neoplasms with the highest incidence in Peru. The great gap in access to primary care reflects the need for effective diagnostic tests. Objetives: To evaluate the diagnostic capacity between colposcopic and cytological tests in the detection of cervix lesion in patients treated at the Alberto Leopoldo Barton Thompson Hospital Complex. Objetives: To evaluate the diagnostic capacity between colposcopic and cytological tests in the detection of cervix lesion in patients treated at the Alberto Leopoldo Barton Thompson Hospital Complex. Material and methods: Study of diagnostic tests that investigated patients who attended the cervical screening clinic of the Alberto Leopoldo Barton Thompson Hospital Complex. Sensitivity (S), specificity (E), predictive values, percentage of agreement and diagnostic odd ratio (ORD) were calculated. Results: 185 patients were studied. The Pap smear's S was 78.9%, its E was 23.2%. The S of colposcopy was 93.3%, its E was 15.8%. The OR for Pap was 1.13 (95% CI [0.53 – 2.41]) and for colposcopy it was 2.62 (95% CI [0.90 – 8.64]). Conclusions: Colposcopy and Pap would present similar diagnostic accuracy as diagnostic tests for cervical intraepithelial lesions. In this context, colposcopy would be more useful in making decisions for early treatment.
Downloads
Metrics
References
Global Cancer Observatory. Cancer Today [Internet]. https://gco.iarc.fr/. [citado 29 de enero de 2023]. Disponible en: https://gco.iarc.fr/
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. mayo de 2021;71(3):209-49.
OMS. Cáncer cervicouterino [Internet]. 2022 [citado 29 de enero de 2023]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/cervical-cancer
Revilla T L. Situación del cáncer en el Perú, 2021. [Internet]. Presentado en teleconferencia presentado en; 2021. Disponible en: https://www.dge.gob.pe/portal/docs/tools/teleconferencia/2021/SE252021/03.pdf
Rerucha CM, Caro RJ, Wheeler VL. Cervical Cancer Screening. Am Fam Physician. 1 de abril de 2018;97(7):441-8.
Sankaranarayanan R, Budukh AM, Rajkumar R. Effective screening programmes for cervical cancer in low- and middle-income developing countries. Bull World Health Organ. 2001;79(10):954-62.
Equipo Técnico de la Dirección de Prevención y Control de Cáncer, Ministerio de Salud, Instituto Nacional de Enfermedades Neoplásicas. PLAN NACIONAL DE PREVENCIÓN Y CONTROL DE CÁNCER DE CUELLO UTERINO 2017 - 2021 [Internet]. 2017. Disponible en: http://bvs.minsa.gob.pe/local/MINSA/4232.pdf
Centro Nacional de Epidemiología, Prevención y Control de Enfermedades, Ministerio de Salud. Análisis de la situación del cáncer en el Perú [Internet]. 2020. Disponible en: http://bvs.minsa.gob.pe/local/MINSA/5158.pdf
Gage JC, Ferreccio C, Gonzales M, Arroyo R, Huivı́n M, Robles SC. Follow-up care of women with an abnormal cytology in a low-resource setting. Cancer Detect Prev. enero de 2003;27(6):466-71.
Paz-Soldán VA, Bayer AM, Nussbaum L, Cabrera L. Structural barriers to screening for and treatment of cervical cancer in Peru. Reprod Health Matters. diciembre de 2012;20(40):10.1016/S0968-8080(12)40680-2.
Silvana L, Jennifer Winkler. Prevención del cáncer cervicouterino en el Perú: Lecciones aprendidas del proyecto demostrativo TATI [Internet]. Organización Panamericana de la Salud, 2006; 2006. Disponible en: https://www3.paho.org/spanish/ad/dpc/nc/pcc-cc-tati-rpt.pdf
Najib FS, Hashemi M, Shiravani Z, Poordast T, Sharifi S, Askary E. Diagnostic Accuracy of Cervical Pap Smear and Colposcopy in Detecting Premalignant and Malignant Lesions of Cervix. Indian J Surg Oncol. septiembre de 2020;11(3):453-8.
Samillan Salhuana CJ. Validez diagnóstica de la citología en la detección de lesiones neoplásicas de cuello uterino en el Instituto Nacional Materno Perinatal durante el año 2019. Rev Peru Investig Materno Perinat. 4 de abril de 2022;10(4):41-50.
Huamán Naula A. Evaluación Citológica, Colposcópica e Histológica de Lesiones de Cuello Uterino en Mujeresde la Selva Peruana. Acta Cancerológica. 2007;35(1):15-8.
Akinwuntan AL, Adesina OA, Okolo CA, Oluwasola OA, Oladokun A, Ifemeje AA, et al. Correlation of cervical cytology and visual inspection with acetic acid in HIV-positive women. J Obstet Gynaecol J Inst Obstet Gynaecol. agosto de 2008;28(6):638-41.
Kumar Gv, Prabhu A, Sebastian A. P16INK4a/ki67 immunocytochemistry in improving the predictive value for high grade cervical intraepithelial (≥CIN2) neoplasia in pap smear. J Cytol. 2021;38(4):180.
Cuzick J, Clavel C, Petry KU, Meijer CJLM, Hoyer H, Ratnam S, et al. Overview of the European and North American studies on HPV testing in primary cervical cancer screening. Int J Cancer. 1 de septiembre de 2006;119(5):1095-101.
Świderska-Kiec J, Czajkowski K, Zaręba-Szczudlik J, Kacperczyk-Bartnik J, Bartnik P, Romejko-Wolniewicz E. Comparison of HPV Testing and Colposcopy in Detecting Cervical Dysplasia in Patients With Cytological Abnormalities. In Vivo. 2020;34(3):1307-15.
Nkwabong E, Laure Bessi Badjan I, Sando Z. Pap smear accuracy for the diagnosis of cervical precancerous lesions. Trop Doct. enero de 2019;49(1):34-9.
Ruan Y, Liu M, Guo J, Zhao J, Niu S, Li F. Evaluation of the accuracy of colposcopy in detecting high-grade squamous intraepithelial lesion and cervical cancer. Arch Gynecol Obstet. diciembre de 2020;302(6):1529-38.
Najib FS, Hashemi M, Shiravani Z, Poordast T, Sharifi S, Askary E. Diagnostic Accuracy of Cervical Pap Smear and Colposcopy in Detecting Premalignant and Malignant Lesions of Cervix. Indian J Surg Oncol. septiembre de 2020;11(3):453-8.
Tames AS, Viamonte KR. Correlación cito-colpo-histológica en lesiones premalignas del cuello uterino en el Hospital Básico Píllaro en Ecuador. Rev Cuba Obstet Ginecol [Internet]. 22 de diciembre de 2017 [citado 16 de abril de 2021];43(3). Disponible en: http://revginecobstetricia.sld.cu/index.php/gin/article/view/234
Venegas G, Bendezu-Quispe G, Urrunaga-Pastor D, Alzamora MC, Franco-Liñan C, Benites-Zapata VA. Factores asociados al resultado citológico positivo en pruebas de Papanicolau en mujeres atendidas en la Liga peruana de lucha contra el cáncer. Rev Cuerpo Méd Hosp Nac Almanzor Aguinaga Asenjo. 31 de diciembre de 2021;14(4):484-90.
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2024 Silvia R. Chacón-Byrne, William J. Araujo-Banchon, Rosa B. Gutarra-Vilchez
This work is licensed under a Creative Commons Attribution 4.0 International License.