Primary Burkitt lymphoma of the cecal appendix: Case report
DOI:
https://doi.org/10.35434/rcmhnaaa.2023.162.1891Keywords:
Primary lymphoma, appendix, Burkitt lymphomaAbstract
Introduction: Primary lymphoma of the appendix occurs in 0.015% of all malignant neoplasms of the appendix. The most frequent clinical manifestation is acute appendicitis, and pathological analysis is very important. Case report: Primary lymphoma of the cecal appendix, a 38-year-old man was admitted with acute appendicitis. Macroscopic histopathological study shows diffusely thickened white appendage wall. Microscopically: high-grade Burkitt lymphoma, ACL, CD20, CD10 positive, KI 67 positive 95%, CD3, BCL2, EBV negative. Postoperative: thoracic abdominal tomography showed a tumor in the right iliac fossa without lesions or adenopathies in the abdomen and thorax. The patient was treated with two courses of chemotherapy and a control abdominal CT was performed at 6 months, which showed the initial tumor. At 6 months the patient is stable and controlled. Conclusion: The value of the histopathological study in cecal appendages is emphasized in the presence of primary cecal lymphomas.
This case emphasizes the value of the histopathological study in the cecal appendages in the presence of primary cecal lymphomas.
Key Words: Primary lymphoma, appendix, Burkitt lymphoma [DeCS/MESH].
Downloads
Metrics
References
Burka JS. Lymphoproliferative disorders of the gastrointestinal tract: a review and pragmatic guide to diagnosis. Arch Pathol Lab Med 2011;135: 1283-97. https://pubmed.ncbi.nlm.nih.gov/21970484/
Ayub A, Santana-Rodríguez N, Raad W, Bhora FY. Primary appendiceal lymphoma: clinical characteristics and outcomes of 116 patients. J Surg Res 2017;207: 174–80. doi: 10.1016/j.jss.2016.08.079
de Morais S, Mikhael B, Németh S, Paulo I, de Barros E, Lima O. Burkitt’s lymphoma presenting as acute appendicitis: a case report Journal of Surgical Case Reports, 2018;6:1–3. doi: 10.1093/jscr/rjy131
Peng JC, Zhong L, Ran ZH. Primary lymphomas in the gastrointestinal tract. J Dig Dis. 2015 ;16(4):169-76. doi: 10.1111/1751-2980.12234
Gurney KA, Cartwright RA. Increasing incidence and descriptive epidemiology of extranodal non-Hodgkin lymphoma in parts of England and Wales. Hematol J 2002; 3:95-104. doi: 10.1038/sj.thj.6200154
Fu TY, Wang JS, Tseng HH. Primary Appendiceal Lymphoma Presenting as Perforated Acute Appendicitis. J Chin Med Assoc 2004; 67:629-632 . https://pubmed.ncbi.nlm.nih.gov/15779487/
Watson G: A, Gleeson J , Kell D, Byrne D, De La Harpe-Golden P, Mulsow1 J, Fortune a, Carney D . Non–Hodgkin’s Lymphoma of the Appendix. Cancer and Clinical Oncology 2016; 5,1:1-5. doi: 105539/cco.v5n1p1
Abdalla MF, El-Hennawy HM. Unusual presentation for primary appendiceal lymphoma: a case report. Indian J Surg 2010; 72:289–92. doi: 10.1007/s12262-010-0093-5
García-Norzagaraya J.C., Villalobos-Lópeza J.A., Flores-Nájeraa H, Valle Lealb J.G, García Torres C.D. Linfoma primario de apéndice: reporte de un caso y revisión de la literatura. Rev Gastroenterol Mex. 2019;84(2):254-257. doi: 10.1016/j.rgmx.2018.04.001
NCCN Clinical Practice Guidelines in Oncology. B-Cell Lymphomas Version 2. 2020-July 9 , 2020. National Comprehensive Cancer Network [Internet]: https://www.nccn.org/guidelines/recently-published-guidelines
Swerklow SH, Campo E, Narris NL, Jaffe ES, Pileri SA, Stein H. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Revised 4ta ed. Lyon, France: IARC;2017. International Agency for Research on Cancer [Internet]: https://www.iarc.who.int/news-events/who-classification-of-tumours-of-haematopoietic-and-lymphoid-tissues-2/
Dawson MP, Cornes JS, Morson BC. Primary malignant lymphoid tumours of the intestinal tract. Report of 37 cases with a study of factors influencing prognosis. Br J Surg. 1961; 49:80-9. doi: 10.1002/bjs.18004921319
Cirocchi R, Farinella E, Trastulli S, Cavaliere D, Covarelli P, Listorti C, et al. Surgical treatment of primitive gastrointestinal lymphomas: a systematic review. World J Surg Oncol 2011; 9:145. doi: 10.1186/1477-7819-9-145
Shannon EM, MacQueen IT, Miller JM, Maggard-Gibbons M. Management of primary gastrointestinal non-Hodgkin lymphomas: a population-based survival analysis. J Gastrointest Surg 2016; 20:1141–9. doi: 10.1007/s11605-016-3129-8
Kelly JL,Toothaker SR, Ciminello L, Hoelzer D, Holte H, La Casce AS, et al. Outcomes of patients with Burkitt lymphoma older tan age 40 treated with intensive chemotherapeutic regimens. Clin Lymphoma Myeloma 2009; 9:307-310. doi: 10.3816/CLM.2009.n.060/
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2023 Rakel Cardeña-Mamani, Victor Yep-Gamarra, Luis Concepcion-Urteaga, Elena Alvarado-Leon, Julio Hilario-Vargas, Paul Galván Guillermo
This work is licensed under a Creative Commons Attribution 4.0 International License.
