Expelled hypopharynx myxoid liposarcoma: a rare entity to consider

Authors

  • Katherine Gómez-Rázuri Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.
  • Diógenes Prieto-Huamán Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.
  • Milagros Abad-Licham Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.
  • Juan Astigueta-Pérez Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.

DOI:

https://doi.org/10.35434/rcmhnaaa.2024.171.2200

Keywords:

Liposarcoma, Myxoid, Hypopharynx

Abstract

Introduction: The diagnosis of sarcoma in the head and neck is unusual, so the case of a 53-year-old female patient with myxoid liposarcoma in the hypopharynx is reported due to its rarity in this location. Case of report: Clinically, tumor growth is associated with dysphagia, dysphonia, and obstruction. Imaging characteristics may contribute in a magnetic resonance study; however, the definitive diagnosis is histological and genetic. This diagnosis is often difficult and generally only recognized with recurrences. The treatment of choice is surgical with or without chemotherapy/radiotherapy, with myxoid liposarcoma being particularly radiosensitive. Conclusion: Local recurrence is common, but metastasis seldom occurs. This case contributes to Latin American literature and emphasizes the importance of early recognition of the disease, considering the required histological characteristics.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

Katherine Gómez-Rázuri, Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.

  1. Médico especialista en Anatomía Patológica

Diógenes Prieto-Huamán, Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.

  1. Médico residente de tercer año de Cirugía Oncológica

Milagros Abad-Licham, Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.

  1. Médico sub-especialista en Patología Oncológica

Juan Astigueta-Pérez, Instituto Regional de Enfermedades Neoplásicas del Norte, La Libertad-Perú.

  1. Médico especialista en Cirugía Oncológica

References

Kim YB, Leem DH, Baek JA, Ko SO. Atypical lipomatous tumor/well-differentiated liposarcoma of the gingiva: a case report and review of literature. J Oral Maxillofac Surg. 2014; 72(2): 431-9. doi: 10.1016/j.joms.2013.06.222. Epub 2013 Aug 29. PMID: 23992781

Encinas Tobajas VM, Almeida González C, Marcilla D, Vallejo M, Cano Rodríguez A, Reina Sánchez de Movellán JI, et al. Myxoid liposarcoma: MRI features with histological correlation. Radiologia Engl Ed. 2021; 33(21): 1-10. doi: 10.1016/j.rx.2021.01.005

Murshed KA, Abo Samra H, Ammar A. Well-Differentiated Liposarcoma of the Hypopharynx Exhibiting Myxoid Liposarcoma-like Morphology with MDM2 and DDIT3 Co-Amplification. Head Neck Pathol. 2022; 16(1): 288-293. doi:10.1007/s12105-021-01341-5

El Ouakif F, Decourselle F, Schultheis D. Liposarcome de l'hypopharynx: à propos de deux cas et revue de la littérature [Liposarcoma of the hypopharynx: two case reports and literature review]. Rev Laryngol Otol Rhinol (Bord). 2011; 132(4-5): 245-250. PMID: 22908550

Al-Kadi M, AlOtieschan S, Almahdi MJ, AlHajress R. An Atypical Lipomatous Tumor of the Hypopharynx: Case Report. Cureus. 2022; 14(3): e23348. doi: 10.7759/cureus.23348

Patel J, Ismail M, Fowler N, Maronian N, Faulx A. Ubicación inusual de una neoplasia maligna inusual. ACG Case Reports Journal. 2021; 8(11): e00656. doi: 10.14309/crj.0000000000000656

Wanes P, Nolte DA, Tranesh GA. Hypopharyngeal Dedifferentiated Liposarcoma in the MDM2 Era: A Case Report and Short Review. Case reports in Pathology. 2020: 1-4. doi:10.1155/2020/2968467

Zidar N, Gale N. Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space. Head Neck Pathol. 2022;16(1): 31-39. doi: 10.1007/s12105-021-01405-6

Cárcamo M. Epidemiología y generalidades del tumor de cabeza y cuello. Revista Médica Clínica Las Condes. 2018. 29(4): 388-396. doi: 10.1016/j.rmclc.2018.06.009

Eyermann C, Raguin T, Hemar P, Debry C. Well-differentiated, pedunculated liposarcoma of the hypopharynx. Eur Ann Otorhinolaryngol Head Neck Dis. 2018; 135(1): 63-65. doi: 10.1016/j.anorl.2017.07.001

Riva G, Sensini M, Corvino A, Vittone F, Garzaro M, Pecorari G. Rare Giant Pedunculated Liposarcoma of the Hypopharynx: Case Report and Review of Literature. Journal of Gastrointestinal Cancer. 2016; 47 (4): 449-453. doi: 10.1007/s12029-015-9767-3

Published

2024-05-03

How to Cite

1.
Gómez-Rázuri K, Prieto-Huamán D, Abad-Licham M, Astigueta-Pérez J. Expelled hypopharynx myxoid liposarcoma: a rare entity to consider. Rev. Cuerpo Med. HNAAA [Internet]. 2024 May 3 [cited 2024 Nov. 23];17(1). Available from: http://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/2200

Issue

Section

Case Reports

Categories