Severe rhabdomyolysis in an infant with Multisystem Inflammatory Syndrome Related to COVID-19 (MIS-C)
DOI:
https://doi.org/10.35434/rcmhnaaa.2022.154.1624Keywords:
Rhabdomyolysis, SARS-CoV-2, Multisystem Inflammatory Syndrome in Children (MIS-C), Renal InsufficiencyAbstract
A case of severe rhabdomyolysis associated with multisystem inflammatory syndrome related to COVID-19 (MIS-C) is presented in a one-year 10-month-old boy who presented digestive symptoms, myalgia, weakness, fever, and dark urine. COVID-19 IgM (-) IgG (+) serological test, COVID-19 PCR negative. Initial creatine kinase (CK) presented non-dosable values, with the highest reported level being 517,600 U/L. The creatinine value remained normal throughout the hospitalization. He received human immunoglobulin 2 g/Kg, Methylprednisolone 10 mg/Kg/d, and acetylsalicylic acid to manage MIS-C. Aggressive hydration and urine alkalinization were provided to manage rhabdomyolysis. Positive evolution with discharge after ten days. Few reported cases of rhabdomyolysis are associated with MIS-C and none with such high CK values. Based on the possible complications, performing CK dosing in all patients with MIS-C is suggested routinely.
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Copyright (c) 2023 María del Carmen Valdivia-Tapia, Alicia Marilú Vargas-Vega, Grimaldo Ramirez-Cortez, Nilton Yhuri Carreazo
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