Clinical and histopathological characteristics of peruvian children with craniopharyngioma
DOI:
https://doi.org/10.35434/rcmhnaaa.2023.161.1599Keywords:
Brain Neoplasms, Craniopharyngioma, Hypopituitarism, Neurosurgical Procedures, Radiotherapy, ChildAbstract
Introduction: Craniopharyngiomas are benign tumors, of which up to 50% occur in children. However, there are no studies in Peruvian children. Objective: to describe the clinical and histopathological characteristics of children with craniopharyngioma hospitalized at the Edgardo Rebagliati Martins National Hospital between August 2019 and May 2021. The study: The design is cross-sectional and the data source were medical records. Information on sex, age, surgeries and characteristics related to the first tumor resection surgery were collected. Findings: We included 12 patients. 83.3% were male, at the time of diagnosis the median age was 6 years and visual symptoms predominated, all had hormonal deficiencies after the first resection surgery. Conclusions: three received radiotherapy, one developed malignant transformation and one died. Future prospective studies are necessary.
Downloads
Metrics
References
Tosta-Hernandez PDC, Siviero-Miachon AA, Da Silva NS, Cappellano A, Pinheiro MDM, Spinola-Castro AM. Childhood Craniopharyngioma: A 22-Year Challenging Follow-Up in a Single Center. Horm Metab Res. 2018;50(9):675–82. doi: 10.1055/a-0641-5956.
Liu APY, Tung JYL, Ku DTL, Luk CW, Ling ASC, Kwong DLW, et al. Outcome of Chinese children with craniopharyngioma: a 20-year population-based study by the Hong Kong Pediatric Hematology/Oncology Study Group. Child’s Nerv Syst. 2020;36(3):497–505. doi: 10.1007/s00381-019-04480-x.
Müller HL. Craniopharyngioma. Endocr Rev. 2014;35(3):513–43. doi: 10.1210/er.2013-1115.
Drapeau A, Walz PC, Eide JG, Rugino AJ, Shaikhouni A, Mohyeldin A, et al. Pediatric craniopharyngioma. Child’s Nerv Syst. 2019;35(11):2133–45. doi: 10.1007/s00381-019-04300-2.
Riaz Q, Naeem E, Fadoo Z, Lohano M, Mushtaq N. Intracranial tumors in children: a 10-year review from a single tertiary health-care center. Child’s Nerv Syst. 2019;35(12):2347–53. doi: 10.1007/s00381-019-04260-7.
Enayet AER, Atteya MME, Taha H, Zaghloul MS, Refaat A, Maher E, et al. Management of pediatric craniopharyngioma: 10-year experience from high-flow center. Child’s Nerv Syst. 2021;37(2):391–401. doi: 10.1007/s00381-020-04833-x.
Bereket A. Postoperative and Long-Term Endocrinologic Complications of Craniopharyngioma. Horm Res Paediatr. 2021;93(9–10):497–509. doi: 10.1159/000515347.
Müller HL, Merchant TE, Warmuth-Metz M, Martinez-Barbera JP, Puget S. Craniopharyngioma. Nat Rev Dis Prim. 2019;5(1). doi: 10.1038/s41572-019-0125-9.
Karavitaki N, Brufani C, Warner JT, Adams CBT, Richards P, Ansorge O, et al. Craniopharyngiomas in children and adults: Systematic analysis of 121 cases with long-term follow-up. Clin Endocrinol (Oxf). 2005;62(4):397–409. doi: 10.1111/j.1365-2265.2005.02231.x.
Fouda MA, Scott RM, Marcus KJ, Ullrich N, Manley PE, Kieran MW, et al. Sixty years single institutional experience with pediatric craniopharyngioma: between the past and the future. Child’s Nerv Syst. 2020;36(2):291–6. doi: 10.1007/s00381-019-04294-x.
Sandvik U, Ohlsson M, Edström E. Vascular complications in pediatric craniopharyngioma patients: a case-based update. Child’s Nerv Syst. 2019;35(12):2273–8. doi: 10.1007/s00381-019-04394-8.
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2023 Manuel André Virú-Loza , Bianca Fiorella Miranda-Cabrera, Milagros Ysel Cabrera-Chávez, Héctor Francisco Flores-Nakandakare , Daniel Abraham Canchanya-Balbin
This work is licensed under a Creative Commons Attribution 4.0 International License.