Posterior Reversible Encephalopathy syndrome in allogenic bone marrow transplantation: Case report in a reference hospital of Peru

Authors

  • Susy Bazán-Ruiz Escuela de Medicina, Universidad César Vallejo. Piura, Perú
  • Miguel A. Vences Escuela de Medicina, Universidad César Vallejo. Piura, Perú; Instituto Nacional cardiovascular, EsSalud, Lima, Perú
  • Guido Bendezú-Quispe Universidad Privada Norbert Wiener, Centro de Investigación Epidemiológica en Salud Global, Lima, Perú.
  • Alfredo Wong Unidad de Trasplante de Médula Ósea. Departamento de Hematología. Hospital Nacional Edgardo Rebagliati Martins – EsSalud

DOI:

https://doi.org/10.35434/rcmhnaaa.2024.171.2084

Keywords:

Posterior Leukoencephalopathy Syndrome, Transplantation, Allogenic Transplant, Peru

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a rare neurological complication of allogeneic stem cell transplantation (incidence of 1.1-22%). Usually presents as a disorder of consciousness or encephalopathy, associated in most cases with headache, visual disturbance, Hypertension and epileptic seizures. Literature describes the presence of PRES in patients who have received immunosuppressive agents after Hematopoietic Stem Cells transplantation, including cyclosporine, tacrolimus, and sirolimus, as well as chemotherapy such as cyclophosphamide, vincristine, methotrexate, L-aspar, among others. Two cases of hematological patients with PRES are presented, and a review of the literature on PRES after Hematopoietic Stem Cells transplantation.

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Author Biographies

Susy Bazán-Ruiz, Escuela de Medicina, Universidad César Vallejo. Piura, Perú

1. Médico hematólogo

Miguel A. Vences, Escuela de Medicina, Universidad César Vallejo. Piura, Perú; Instituto Nacional cardiovascular, EsSalud, Lima, Perú

1. Médico neurólogo

Guido Bendezú-Quispe, Universidad Privada Norbert Wiener, Centro de Investigación Epidemiológica en Salud Global, Lima, Perú.

1. Médico Cirujano

Alfredo Wong, Unidad de Trasplante de Médula Ósea. Departamento de Hematología. Hospital Nacional Edgardo Rebagliati Martins – EsSalud

1. Médico hematólogo

References

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Published

2024-04-08

How to Cite

1.
Bazán-Ruiz S, Vences MA, Bendezú-Quispe G, Wong A. Posterior Reversible Encephalopathy syndrome in allogenic bone marrow transplantation: Case report in a reference hospital of Peru. Rev. Cuerpo Med. HNAAA [Internet]. 2024 Apr. 8 [cited 2024 Nov. 27];17(1). Available from: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/2084

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