Fisiología de altura. ¿Afecta la altura a la homeostasis?

Autores/as

  • Cristhian Adolfo Vizcarra–Vizcarra Universidad Nacional de San Agustín, Arequipa, Perú; Hospital Regional Honorio Delgado, Arequipa, Perú
  • Elsa Carolina Pérez–Quispe Universidad Nacional de San Agustín, Arequipa, Perú
  • Luana Edelmira Pilco–Prado Universidad Nacional de San Agustín, Arequipa, Perú
  • José Armando Quispe–Ramos Universidad Nacional de San Agustín, Arequipa, Perú
  • Miguel Ángel Monzón–Gonzáles Universidad Nacional de San Agustín, Arequipa, Perú
  • Gianmarco Alejandro Ramos–Paredes Universidad Nacional de San Agustín, Arequipa, Perú

DOI:

https://doi.org/10.35434/rcmhnaaa.2023.164.1866

Palabras clave:

altitud, fisiología, homeostasis, mal de altura

Resumen

En el mundo, existen miles de personas que viven en ciudades de altura. Esta, genera una reducción de la presión de oxígeno atmosférico e hipoxia hipobárica, ocasionando múltiples cambios en los sistemas fisiológicos. Se ha estudiado bastante, el efecto de la altitud en la función pulmonar, cardíaca y hematológica, durante la exposición aguda o crónica, ocasionando aumento de la ventilación pulmonar, variabilidad en la presión arterial y policitemia. A nivel renal, ocasiona disminución de la tasa de filtración glomerular, que puede desencadenar enfermedad renal crónica. De igual forma, existen cambios en el eje endocrinológico–reproductor, en la función cerebral e incluso gastrointestinal. La mala–adaptación de estos sistemas genera patologías como el mal de montaña agudo y crónico, el edema pulmonar y edema cerebral de altura. En esta revisión se presenta una descripción de los principales cambios vistos en los sistemas fisiológicos tras la exposición a la altura.

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Biografía del autor/a

Cristhian Adolfo Vizcarra–Vizcarra, Universidad Nacional de San Agustín, Arequipa, Perú; Hospital Regional Honorio Delgado, Arequipa, Perú

a. Médico Nefrólogo

Elsa Carolina Pérez–Quispe, Universidad Nacional de San Agustín, Arequipa, Perú

a. Estudiante de medicina

Luana Edelmira Pilco–Prado, Universidad Nacional de San Agustín, Arequipa, Perú

a. Estudiante de medicina

José Armando Quispe–Ramos, Universidad Nacional de San Agustín, Arequipa, Perú

a. Estudiante de medicina

Miguel Ángel Monzón–Gonzáles, Universidad Nacional de San Agustín, Arequipa, Perú

a. Estudiante de medicina

Gianmarco Alejandro Ramos–Paredes, Universidad Nacional de San Agustín, Arequipa, Perú

a. Estudiante de medicina

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26-01-2024

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1.
Vizcarra–Vizcarra CA, Pérez–Quispe EC, Pilco–Prado LE, Quispe–Ramos JA, Monzón–Gonzáles M Ángel, Ramos–Paredes GA. Fisiología de altura. ¿Afecta la altura a la homeostasis?. Rev. Cuerpo Med. HNAAA [Internet]. 26 de enero de 2024 [citado 24 de noviembre de 2024];16(4). Disponible en: http://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1866

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