Eficacia de la resección pancreática con preservación duodenal versus pancreaticoduodenectomía en el tratamiento de la pancreatitis crónica en adultos: Revisión Sistemática y Meta-análisis

Autores/as

  • Sergio Silva-Santisteban Gálvez Escuela de Medicina, Universidad Privada Antenor Orrego, Trujillo, Perú.
  • José Caballero-Alvarado Hospital Regional Docente de Trujillo, Trujillo, Perú.

DOI:

https://doi.org/10.35434/rcmhnaaa.2022.15Supl.%201.1607

Palabras clave:

Pancreatitis crónica, resección pancreática, preservación duodenal, eficacia

Resumen

Introducción: Los estudios que comparan la resección pancreática con preservación duodenal (DPPHR) versus pancreaticoduodenectomía (PD) en el tratamiento de la pancreatitis crónica demuestran diferencias notables, sin embargo, la evidencia actual no es adecuada para establecer la superioridad de estos enfoques. Objetivo: Determinar si la resección pancreática con preservación duodenal es más eficaz que la pancreaticoduodenectomía en el tratamiento de la pancreatitis crónica en adultos. Material y métodos: Se realizó una revisión sistemática identificando y extrayendo datos de siete ensayos clínicos aleatorizados y siete estudios observacionales comparando la eficacia de la resección pancreática con preservación duodenal versus la pancreaticoduodenectomía. Resultados: La hemorragia tuvo una diferencia de medias (MD) de -0.18, IC al 95% de -0.25 – -0.12 y p < 0.00001. El tiempo operatorio tuvo una MD de -1.32, IC al 95% de -2.20 – -0.44 y p = 0.003. Estancia hospitalaria tuvo una MD de -3.94, IC al 95% de -6.16 – -1.71 y p = 0.0005. La insuficiencia endocrina tuvo RR de 0.78, IC al 95% de 0.65 – 0.95 y p = 0.01. Pain Score mostró una MD de -7.39, IC al 95% de -13.05 – -1.74 y p = 0.01. Calidad global de vida, mostró MD de 8.97, IC al 95% de 4.05 – 13.90 y p = 0.0004. Conclusiones: La DPPHR resulta más eficaz que la PD al disminuir el sangrado intraoperatorio, tiempo operatorio, estancia hospitalaria, el riesgo de insuficiencia endocrina y al proporcionar mejor alivio del dolor y calidad de vida. 

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Biografía del autor/a

Sergio Silva-Santisteban Gálvez , Escuela de Medicina, Universidad Privada Antenor Orrego, Trujillo, Perú.

  1. Bachiller en Medicina 

José Caballero-Alvarado, Hospital Regional Docente de Trujillo, Trujillo, Perú.

  1. Doctor en Investigación Clínica y Traslacional

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Publicado

06-10-2022

Cómo citar

1.
Silva-Santisteban Gálvez S, Caballero-Alvarado J. Eficacia de la resección pancreática con preservación duodenal versus pancreaticoduodenectomía en el tratamiento de la pancreatitis crónica en adultos: Revisión Sistemática y Meta-análisis. Rev. Cuerpo Med. HNAAA [Internet]. 6 de octubre de 2022 [citado 30 de noviembre de 2022];15(Supl. 1). Disponible en: http://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1607

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