Clinical features and survival in pediatric oncohematological patients with COVID-19 in a referral Hospital of Peruvian Social Health Insurance, during 2020-2021

Authors

  • Giancarlo Alvarado-Gamarra Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú; Instituto de Investigación Nutricional, Lima, Perú; Red de Eficacia Clínica y Sanitaria, REDECS, Lima, Perú https://orcid.org/0000-0002-7266-5808
  • Jesús Dominguez-Rojas Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
  • Noé Atamari-Anahui Universidad San Ignacio de Loyola, Vicerrectorado de Investigación, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Lima, Perú
  • Vanessa Zarate-Campos Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú
  • Sarah Fernández Suárez Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú
  • Eva Vásquez-Gamarra Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú
  • Ninoska Rojas-Soto Unidad de Hematología Pediátrica. Hospital Nacional Edgardo Rebagliati Martins. Lima, Perú
  • Raquel Garcés-Ghilardi Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú
  • Matilde Estupiñan-Vigil Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

DOI:

https://doi.org/10.35434/rcmhnaaa.2023.161.1702

Keywords:

COVID-19, Neoplasms, leukemia, Child, Pediatrics, Peru

Abstract

Introduction: In Latin America, there are few studies and heterogeneous results on pediatric oncohematology patients with COVID-19. Objective: To describe the clinical characteristics and survival of pediatric oncohematology patients with COVID-19 in a hospital in Lima-Peru, 2020-2021. Methods: Retrospective longitudinal study of hospitalized patients under 14 years of age. The data was collected from the medical records. Results: We included 30 patients, mostly men and schoolchildren, predominantly fever, respiratory and gastrointestinal symptoms, hematological neoplasia, and advanced oncological disease. The majority developed mild-moderate disease, but they also presented severe evolution requiring critical areas, with high mortality in hospitalization (13.3%) and low survival during follow-up (at 526 days, 59.26%, 95% CI 36 .53 to 76.20%). Survival increased with the start of chemotherapy, and decreased in patients in palliative condition, with respiratory support and shock. Conclusion: Most developed mild-moderate disease. However, SARS-CoV-2 can also cause severe involvement, death, and poor survival in oncohematological patients.

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Author Biographies

Giancarlo Alvarado-Gamarra, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú; Instituto de Investigación Nutricional, Lima, Perú; Red de Eficacia Clínica y Sanitaria, REDECS, Lima, Perú

1. Médico especialista en Pediatra, maestro en Epidemiología Clínica.

Jesús Dominguez-Rojas, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.

1. Médico especialista en Medicina Pediátrica Intensiva.

Noé Atamari-Anahui, Universidad San Ignacio de Loyola, Vicerrectorado de Investigación, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Lima, Perú

1. Médico especialista en Pediatria

Vanessa Zarate-Campos, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

1. Médico especialista en Pediatria.

Sarah Fernández Suárez, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

1. Médico especialista en Pediatria

Eva Vásquez-Gamarra, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

1. Médico especialista en Pediatria

Ninoska Rojas-Soto, Unidad de Hematología Pediátrica. Hospital Nacional Edgardo Rebagliati Martins. Lima, Perú

1. Médico especialista en Hematología

Raquel Garcés-Ghilardi, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

1. Médico especialista en Pediatria

Matilde Estupiñan-Vigil, Servicio de Pediatría Clínica. Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

1. Médico especialista en Pediatria, doctor en Medicina.

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Published

2023-06-07

How to Cite

1.
Alvarado-Gamarra G, Dominguez-Rojas J, Atamari-Anahui N, Zarate-Campos V, Fernández Suárez S, Vásquez-Gamarra E, Rojas-Soto N, Garcés-Ghilardi R, Estupiñan-Vigil M. Clinical features and survival in pediatric oncohematological patients with COVID-19 in a referral Hospital of Peruvian Social Health Insurance, during 2020-2021. Rev. Cuerpo Med. HNAAA [Internet]. 2023 Jun. 7 [cited 2024 Nov. 23];16(1):51-7. Available from: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1702

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