Características clínicas y supervivencia en pacientes pediátricos oncohematológicos con COVID-19 en un hospital de referencia del Seguro Social de Salud del Perú, durante el 2020-2021
DOI:
https://doi.org/10.35434/rcmhnaaa.2023.161.1702Palabras clave:
COVID-19, Neoplasias, Leucemia, Niño, Pediatría, PerúResumen
Introducción: En Latinoamérica, existen pocos estudios y resultados heterogéneos sobre pacientes pediátricos oncohematológicos con COVID-19. Objetivo: Describir las características clínicas y la supervivencia de pacientes pediátricos oncohematológicos con COVID-19 en un hospital de Lima-Perú, 2020-2021. Métodos: Estudio longitudinal retrospectivo de pacientes menores de 14 años hospitalizados. Los datos se recolectaron de las historias clínicas. Resultados: Incluimos 30 pacientes, mayoría hombres y escolares, predominando la fiebre, síntomas respiratorios y gastrointestinales, la neoplasia hematológica, y la enfermedad oncológica avanzada. La mayoría desarrolló enfermedad leve-moderada, pero también presentaron evolución severa con requerimiento de soporte crítico, con mortalidad alta en hospitalización (13,3%) y baja supervivencia durante el seguimiento (a los 526 días, 59,26%, IC95% 36,53 a 76,20%). La supervivencia aumentó con reinicio de la quimioterapia , y disminuyó en pacientes de condición paliativa, con soporte respiratorio y shock. Conclusiones: La mayoría desarrolló enfermedad leve-moderada. Sin embargo, el SARS-CoV-2 también puede causar afectación severa, muerte y baja supervivencia en pacientes oncohematológicos.
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Derechos de autor 2023 Giancarlo Alvarado-Gamarra, Jesús Dominguez-Rojas, Noé Atamari-Anahui, Vanessa Zarate-Campos, Sarah Fernández Suárez, Eva Vásquez-Gamarra, Ninoska Rojas-Soto, Raquel Garcés-Ghilardi, Matilde Estupiñan-Vigil
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.