Spinal Bone Lymphoma with Intraspinal Extension: Case Report

Authors

  • John Vargas-Urbina Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú.
  • Raúl Martinez-Silva Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú.
  • Eduardo Laos-Plasier Servicio de Neurotrauma y Columna, Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú
  • Alfonso Basurco-Carpio Servicio de Neurotrauma y Columna, Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú

DOI:

https://doi.org/10.35434/rcmhnaaa.2024.171.2171

Keywords:

Lymphoma, non-Hodgkin lymphoma, lymphoma AIDS-related, spinal diseases, surgical decompression

Abstract

Introduction: Spinal bone lymphoma is a rare disease, with diffuse large B-cell lymphoma being the most common subtype. It is usually a late manifestation of a systemic disease. Its management is multidisciplinary, including surgery, chemotherapy and radiotherapy. Clinical case: A 40-year-old woman, with human immunodeficiency virus infection, miliary tuberculosis monoresistant isoniazid, with disease period of 7 month with progressive motor and sensory deficit in addition to sphincter dysfunction. The contrasted MRI shows a left vertebral and paravertebral tumor that invades spinal canal through left T2/T3 foramina with spinal cord compression. Laminectomy T2 and T3 plus total resection of tumor plus spinal fixation is performed. The patient progressively recovered the motor deficit and began chemotherapy with a good response. Conclusion: The spinal bone lymphoma is an infrequent etiology of bone tumor of the spine, which requires multidisciplinary management.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

John Vargas-Urbina, Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú.

1. Médico Neurocirujano

Raúl Martinez-Silva, Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú.

1. Médico Residente

Eduardo Laos-Plasier, Servicio de Neurotrauma y Columna, Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú

1. Médico Neurocirujano

Alfonso Basurco-Carpio, Servicio de Neurotrauma y Columna, Departamento de Neurocirugía, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú

1. Médico Neurocirujano

References

Wang Y, Li J, Wei R, Liu C, Nataraj A, Yan J. Prognostic Factors Associated With Bone Lymphoma Primarily Presenting in the Spine. Spine. 2019;44(3):185-194. doi:10.1097/BRS.0000000000002844

Jawad MU, Schneiderbauer MM, Min ES, Cheung MC, Koniaris LG, Scully SP. Primary lymphoma of bone in adult patients. Cancer. 2010;116(4):871-879. doi:10.1002/cncr.24828

Hashi S, Goodwin CR, Ahmed AK, Sciubba DM. Management of extranodal lymphoma of the spine: a study of 30 patients. CNS Oncol. 2018;7(2):CNS11. doi:10.2217/cns-2017-0033

Koeller KK, Shih RY. Extranodal Lymphoma of the Central Nervous System and Spine. Radiol Clin North Am. 2016;54(4):649-671. doi:10.1016/j.rcl.2016.03.003

Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015: Cancer Statistics, 2015. CA Cancer J Clin. 2015;65(1):5-29. doi:10.3322/caac.21254

Love JG. LYMPHOMAS OF SPINAL EPIDURAL SPACE. Arch Surg. 1954;69(1):66. doi:10.1001/archsurg.1954.01270010068010

Thomas AG, Vaidhyanath R, Kirke R, Rajesh A. Extranodal Lymphoma From Head to Toe: Part 1, The Head and Spine. Am J Roentgenol. 2011;197(2):350-356. doi:10.2214/AJR.10.7266

Haque S, Law M, Abrey LE, Young RJ. Imaging of Lymphoma of the Central Nervous System, Spine, and Orbit. Radiol Clin North Am. 2008;46(2):339-361. doi:10.1016/j.rcl.2008.04.003

Kim H, Kim D, Kim S. Primary Malignant Lymphoma Presenting as an Isolated Epidural Mass. Diagnostics. 2022;12(10):2462. doi:10.3390/diagnostics12102462

Fisher CG, Schouten R, Versteeg AL, et al. Reliability of the Spinal Instability Neoplastic Score (SINS) among radiation oncologists: an assessment of instability secondary to spinal metastases. Radiat Oncol. 2014;9(1):69. doi:10.1186/1748-717X-9-69

Fourney DR, Frangou EM, Ryken TC, et al. Spinal Instability Neoplastic Score: An Analysis of Reliability and Validity From the Spine Oncology Study Group. J Clin Oncol. 2011;29(22):3072-3077. doi:10.1200/JCO.2010.34.3897

Zheng J, Wang M, Wan S, et al. Isolated Primary Non-Hodgkin’s Lymphoma of the Thoracic Spine: A Case Report with a Review of the Literature. J Int Med Res. 2010;38(4):1553-1560. doi:10.1177/147323001003800440

Chang CM, Chen HC, Yang Y, Wang RC, Hwang WL, Teng CLJ. Surgical decompression improves recovery from neurological deficit and may provide a survival benefit in patients with diffuse large B-cell lymphoma-associated spinal cord compression: a case-series study. World J Surg Oncol. 2013;11(1):90. doi:10.1186/1477-7819-11-90

Tsai YH, Kuo TY, Wu KL, Chen CM, Chung YC, Huang MS. Coexistence of intrathoracic lymphoma and pulmonary tuberculosis. Eur Respir J. 2013;42(Suppl 57):P4452.

Campos M, Urrutia J, Zamora T, et al. The Spine Instability Neoplastic Score: an independent reliability and reproducibility analysis. Spine J. 2014;14(8):1466-1469. doi:10.1016/j.spinee.2013.08.044

Published

2024-04-14

How to Cite

1.
Vargas-Urbina J, Martinez-Silva R, Laos-Plasier E, Basurco-Carpio A. Spinal Bone Lymphoma with Intraspinal Extension: Case Report . Rev. Cuerpo Med. HNAAA [Internet]. 2024 Apr. 14 [cited 2024 Nov. 21];17(1). Available from: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/2171

Issue

Section

Case Reports

Categories