Polycystic parotid disease (polycystic sclerosing adenosis associated with dysgenetic polycystic disease): Case report.

Authors

  • José Luis Cabanillas-Lapa Servicio de Anatomía Patológica, Hospital Nacional Dos de Mayo, Lima, Perú
  • Stephania Paredes-Yauri Servicio de Anatomía Patológica, Hospital Nacional Dos de Mayo, Lima, Perú
  • Wilmer Silva-Caso School of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru; Laboratorio de Biomedicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú

DOI:

https://doi.org/10.35434/rcmhnaaa.2023.161.1337

Keywords:

Benign neoplasm, Parotid Gland, Adenoma

Abstract

Introduction: Polycystic sclerosing adenosis / adenoma (SPA) is accepted as a very rare new benign neoplastic entity of the salivary glands that generally involves the parotid gland. Dysgenetic polycystic disease is another rare entity with histology similar to SPA and that also affects the parotid gland more frequently. Case report: The case of a 28-year-old woman with increased volume of the right parotid gland of approximately 3 years of evolution is presented, whose histopathological analysis suggested the diagnosis of Polycystic Sclerosing Adenosis / adenoma associated with Polycystic Dysgenetic Disease of the right parotid gland. The patient received surgical treatment of total parotidectomy with preservation of the facial nerve. At the moment with remission of the disease.

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Author Biographies

José Luis Cabanillas-Lapa, Servicio de Anatomía Patológica, Hospital Nacional Dos de Mayo, Lima, Perú

1. Médico Patólogo-Oncólogo

Stephania Paredes-Yauri , Servicio de Anatomía Patológica, Hospital Nacional Dos de Mayo, Lima, Perú

1. Médica Residente de Anatomía Patológica.

Wilmer Silva-Caso, School of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias Aplicadas, Lima, Peru; Laboratorio de Biomedicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú

1. Médico Investigador Renacyt

References

Skálová A, Gnepp DR, Lewis JS Jr, Hunt JL, Bishop JA, Hellquist H, et al. Newly Described Entities in Salivary Gland Pathology. Am J Surg Pathol. 2017 Aug;41(8):e33-e47. DOI: 10.1097/PAS.0000000000000883

Bishop JA, Gagan J, Baumhoer D, McLean-Holden AL, Oliai BR, Couce M, et al. Sclerosing Polycystic "Adenosis" of Salivary Glands: A Neoplasm Characterized by PI3K Pathway Alterations More Correctly Named Sclerosing Polycystic Adenoma. Head Neck Pathol. 2020 Sep;14(3):630-636. DOI: 10.1007/s12105-019-01088-0

World Health Organization Classification of Tumours (WHO). El-Naggar A., Chan J., Grandis J., Takata T., Slootweg P. Classification of neck and head tumours. 4TH edition; 2017. p195.

Skálová A, Gnepp DR, Simpson RH, Lewis JE, Janssen D, Sima R, et al. Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor (HUMARA) locus as a marker. Am J Surg Pathol. 2006 Aug;30(8):939-44 DOI: 10.1097/00000478-200608000-00002

Smith BC, Ellis GL, Slater LJ, Foss RD. Sclerosing polycystic adenosis of major salivary glands. A clinicopathologic analysis of nine cases. Am J Surg Pathol. 1996 Feb;20(2):161-70. DOI: 10.1097/00000478-199602000-00004

Gnepp DR, Wang LJ, Brandwein-Gensler M, Slootweg P, Gill M, Hille J. Sclerosing polycystic adenosis of the salivary gland: a report of 16 cases. Am J Surg Pathol. 2006 Feb;30(2):154-64. DOI: 10.1097/01.pas.0000186394.64840.1d

Barnes L, Chiosea S, Seethala R. Head and Neck Pathology. Demos Medical Publishing. New York: 2011.3: P54

Volavsek M. Head and Neck Pathology. Springer. Switzerland: 2016. P382-383.

Kumar KA, Mahadesh J, Setty S. Dysgenetic polycystic disease of the parotid gland: Report of a case and review of the literature. J Oral Maxillofac Pathol. 2013 May;17(2):248-52. DOI: 10.4103/0973-029X.119744

Kahraman D, Yalavac P, Akar E, Özen Ö, Günhan Ö. Coexistence of sclerosing polycystic adenosis and dysgenetic polycystic disease of parotid, Report of a case. Indian J Pathol Microbiol. 2020 Jan-Mar;63(1):109-111. DOI: 10.4103/IJPM.IJPM_502_18

Mercado V, Mercado J, García S, Loyola J, Heller F, Vallejos H. Adenosis poliquística esclerosante de la glándula parótida. Rev. Otorrinolaringol. Cir. Cabeza Cuello. 2009 Abr; 69: 41-44

Guledgud M, Patil K, D’souza R. Polycystic Parotid Disease: A Rare Case Report. International Journal of Dental Sciences and Research, 2014, Vol. 2, No. 6, 161-163.

Published

2023-06-04

How to Cite

1.
Cabanillas-Lapa JL, Paredes-Yauri S, Silva-Caso W. Polycystic parotid disease (polycystic sclerosing adenosis associated with dysgenetic polycystic disease): Case report. Rev. Cuerpo Med. HNAAA [Internet]. 2023 Jun. 4 [cited 2024 Nov. 24];16(1):122-5. Available from: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1337

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Case Reports

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