Linfoma/leucemia de células T del adulto: Un desafío pendiente

Autores/as

  • Carolina Álvarez Servicio de Oncología Médica, Departamento de Oncología y Radioterapia, Hospital Nacional Edgardo Rebagliati Martins, EsSalud. Lima, Perú; Unidad de Investigación en HTLV-1, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia. Lima, Perú; Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad Ricardo Palma. Lima, Perú
  • Brady Beltran Servicio de Oncología Médica, Departamento de Oncología y Radioterapia, Hospital Nacional Edgardo Rebagliati Martins, EsSalud. Lima, Perú; 3. Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad Ricardo Palma. Lima, Perú.

DOI:

https://doi.org/10.35434/rcmhnaaa.2023.164.2189

Palabras clave:

Virus Linfotrópico T Tipo 1 Humano, Leucemia-Linfoma de Células T del Adulto, Epidemiología, Protocolos Antineoplásicos

Resumen

El linfoma/leucemia de células T del adulto (ATLL) es una neoplasia de células T post tímicas de mal pronóstico y de difícil manejo. Se ha asociado etiológicamente al virus linfotrópico de células T humanas tipo 1 (HTLV-1), retrovirus que se ha identificado en zonas endémicas como Japón, África oriental, las islas del Caribe y Sudamérica. En el Perú, se estima que de 1 a 2% de la población es portadora del virus. El riesgo vital de desarrollar ATLL para un portador de HTLV-1 es de 5%. Dada la endemicidad de esta infección en nuestro medio y el pobre pronóstico del ATLL, resultan necesarias alternativas terapéuticas e intervenciones preventivas. En esta revisión, exploramos las características clínicas, epidemiológicas y las opciones de tratamiento del ATLL.

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Biografía del autor/a

Carolina Álvarez, Servicio de Oncología Médica, Departamento de Oncología y Radioterapia, Hospital Nacional Edgardo Rebagliati Martins, EsSalud. Lima, Perú; Unidad de Investigación en HTLV-1, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia. Lima, Perú; Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad Ricardo Palma. Lima, Perú

1. Médico

Brady Beltran , Servicio de Oncología Médica, Departamento de Oncología y Radioterapia, Hospital Nacional Edgardo Rebagliati Martins, EsSalud. Lima, Perú; 3. Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad Ricardo Palma. Lima, Perú.

1. Médico

Citas

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09-02-2024

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1.
Álvarez C, Beltran B. Linfoma/leucemia de células T del adulto: Un desafío pendiente. Rev. Cuerpo Med. HNAAA [Internet]. 9 de febrero de 2024 [citado 2 de mayo de 2024];16(4). Disponible en: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/2189

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