Tuberculosis pulmonar imitando metástasis pulmonares
DOI:
https://doi.org/10.35434/rcmhnaaa.2025.184.2947Palabras clave:
tuberculosis, lung, metastaticResumen
Introduction: Tuberculosis (TB) is an infectious disease caused by the Mycobacterium tuberculosis. The disease can present in the chest as pulmonary infiltrates and/or mediastinal lymphadenopathy, The TB is a disease who has a special ability to mimic other pathologies, including malignancies.
Case report:
We present the case of a 36-year-old male with bilateral symbrachydactyly, residing in Ecuador. The patient presented with a two-month history of dry cough. A non-contrast chest CT scan revealed multiple bilateral subcentimeter pulmonary nodules. Due to the high suspicion of a metastatic disease, a biopsy of one of the pulmonary nodules through surgical biopsy was performed, showing caseating granulomas in the histopathological study. A multidisciplinary committee decided to iniciate tuberculosis treatment based on the standard 2HREZ/4HR regimen, in the following weeks the patient showed significant symptomatic improvement and positive tuberculosis culture at 12 weeks. A follow-up CT scan at six months showed complete resolution of the pulmonary lesions.
Conclusion
In countries with a high incidence of tuberculosis, clinical suspicion is sufficient to start specific treatment until cultures confirm the disease.
Descargas
Referencias
Hammen I. Tuberculosis mimicking lung cancer. Respir Med Case Rep. 2015;16:45-7. doi: 10.1016/j.rmcr.2015.06.007
Van Dyck P, Vanhoenacker FM, Van den Brande P, De Schepper AM. Imaging of pulmonary tuberculosis. Eur Radiol. 2003;13(8):1771-85. doi: 10.1007/s00330-002-1612-y
Pilaniya V, Gera K, Kunal S, Shah A. Pulmonary tuberculosis masquerading as metastatic lung disease. Eur Respir Rev. 2016;25(139):97-8. doi: 10.1183/16000617.00002315
Lee HS, Oh JY, Lee JH, Yoo CG, Lee CT, Kim YW, Han SK, Shim YS, Yim JJ. Response of pulmonary tuberculomas to anti-tuberculous treatment. Eur Respir J. 2004;23(3):452-5. doi: 10.1183/09031936.04.00087304
Winer-Muram HT, Rubin SA. Thoracic complications of tuberculosis: J Thorac Imaging [Internet]. abril de 1990 [citado el 22 de junio de 2024];5(2):46–63. Disponible en: http://journals.lww.com/00005382-199004000-00008
Hang TX, Fang G, Huang Y, Hu CM, Chen W. Misdiagnosis of a multi-organ involvement hematogenous disseminated tuberculosis as metastasis: a case report and literature review. Infect Dis Poverty. 2020 Jun 9;9(1):66. doi: 10.1186/s40249-020-00681-8.
Morikawa K, Misumi S, Fukuda T. A case of pulmonary tuberculosis with multiple nodules mimicking lung metastases. BJR Case Rep. 2019 Apr 1;5(3):20180124. doi: 10.1259/bjrcr.20180124
Şahin C, Camurcuoglu E, Agridag B, Durmaz S. Casos de tuberculosis pulmonar y esquelética comprobados mediante biopsia guiada por imagen que simulan malignidad. J Surg Med. 2020;4(9):761-5. doi:10.28982/josam.784382.
Xiang Y, Huang C, He Y, Zhang Q. Cancer or Tuberculosis: A Comprehensive Review of the Clinical and Imaging Features in Diagnosis of the Confusing Mass. Front Oncol. 2021 Apr 28;11:644150. doi: 10.3389/fonc.2021.644150.
Kant S, Saheer S, Prakash V, Hasan G, Jabeed P, Husain N. Bilateral nodular pulmonary tuberculomas simulating metastatic disease. BMJ Case Rep. 2011 Apr 13;2011:bcr1120103539. doi: 10.1136/bcr.11.2010.3539.
Paci M, Cavazza A, Ferrari G, Filice A, Sgarbi G. Image of the month. Pulmonary tuberculosis mimicking lung metastasis. J Thorac Oncol. 2008 Jun;3(6):660-1. doi: 10.1097/JTO.0b013e3181757ad4.
Ariyürek MO, Karçaaltincaba M, Demirkazik FB, Akay H, Gedikoglu G, Emri S. Bilateral multiple pulmonary tuberculous nodules mimicking metastatic disease. Eur J Radiol. 2002 Oct;44(1):33-6. doi: 10.1016/s0720-048x(01)00402-8.
Carrasco Sánchez M, Solís García E, Mejías Sosa L, García-Salmones Martín M. Tuberculosis Simulating Lung Cancer. Open Respir Arch. 2023 Mar 22;5(3):100244. doi: 10.1016/j.opresp.2023.100244.
Descargas
Publicado
Número
Sección
Categorías
Licencia
Derechos de autor 2026 Nathalie Pinos, Jose David Cardoso, Oswaldo Leon Cabrera

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.




